Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I’m a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients.
In this podcast, Warrick Bishop discusses the biochemical processes involved in statin therapy, particularly how it affects cholesterol production. He explains the conversion pathway from acetyl CoA to HMG CoA, mevalonic acid, and ultimately cholesterol. The conversation highlights the role of coenzyme Q10 (ubiquinone), which is essential for energy formation in cells and may be linked to muscle-related side effects from statins. A recent study from 2022 investigated the relationship between coenzyme Q10 levels and statin-related muscle symptoms but found no significant correlation or benefit from supplementation. Despite this, Bishop suggests that individual patients might still benefit from trying coenzyme Q10. He also introduces benberdomic acid, a new agent that works upstream of the statin pathway and may provide an alternative for those experiencing muscle aches due to statin use. The podcast encourages listeners to consider their experiences with these treatments and to reach out with feedback or suggestions for future topics. Bishop concludes with a positive message about living well.
Takeaways:
- Statin Therapy Pathway: Statins influence a biochemical pathway that converts acetyl CoA into cholesterol, impacting various compounds along the way.
- Vitamin K Compounds: The discussion includes vitamin K1 (phylloquinones) and vitamin K2 (menaquinones), highlighting their significance in health.
- Ubiquinone (Coenzyme Q10): Ubiquinone, also known as coenzyme Q10, plays a crucial role in cellular energy production, particularly in the mitochondria.
- Muscle Symptoms and CoQ10: There is a potential link between diminished levels of coenzyme Q10 and muscle aches associated with statin use.
- Research Study Overview: A 2022 study involved 80 participants with mild statin-related muscle symptoms to evaluate the relationship between coenzyme Q10 levels and their symptoms.
- Study Findings: The study found no significant connection between coenzyme Q10 levels and muscle symptoms, nor did supplementation show a notable impact on levels.
- Individual Variability: While the study results were general, individual patients may still benefit from coenzyme Q10 supplementation, particularly if they experience muscle pain.
- Benberdobic Acid: This new agent operates upstream in the same enzymatic pathway as statins and may offer an alternative solution for muscle-related side effects without affecting coenzyme Q10 levels.
- Liver-Specific Action: Benberdobic acid’s mechanism is limited to the liver, potentially reducing systemic side effects associated with statin therapy.
- Open Dialogue: Doctor Bishop encourages listener feedback and suggestions for future podcast topics, emphasizing the importance of ongoing communication regarding health and treatment options.
Australia, like the rest of the western world, has a heart problem.
Over 9 million people around the world die from heart disease every year.
Every 10 minutes, someone in Australia suffers a heart attack. And 21 lives are lost daily because of it.
The devastating fact in all of this is…
Almost every one of those cases could have been prevented.
This podcast is for anyone who wants to improve their health literacy and gain information to help them make the best decisions about their risk of heart attack, their cholesterol, blood pressure, risk of diabetes, weight loss and general health. Join me on my personal mission journey to prevent Heart Attack on a global scale. If you like this podcast, I would be honoured by a 5-star review and appreciate if you let your friends and family know about this podcast; you may even save the life of someone you love!
Are You at Risk of a Sudden Heart Attack? How Healthy is Your Heart? Really?
Heart disease is the #1 killer in the Western World. In Australia, someone dies every 28 minutes from heart disease. That’s 51 people a day. In the US, someone has a heart attack every 40 SECONDS! Fortunately, many heart attacks are preventable. However, regular exercise and eating healthy are no guarantee you won’t succumb to this silent killer.
- 94% of Australians have at least One Risk Factor for heart disease.
- 59% of Australians have been Touched by heart disease.
- Yet only 3% of Australians have had a Full Heart-Health Assessment in the past 12 months.
Do the free heart check today at www.virtualheartcheck.com.au
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The Healthy Heart Network is designed to help members:
- understand the present state of their heart’s health
- recognise their current level of risk of suffering a heart attack
- Learn the positive steps they can take to improve their situation
Visit https://healthyheartnetwork.com/ and click on the JOIN THE FAMILY BUTTON
