EP416: Highlights of WCCL June 2025

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Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I’m a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients.

Dr. Warrick Bishop, a cardiologist and CEO of the Healthy Heart Network, shares insights from the 4th World Congress of Clinical Lipidology. He highlights that LDL cholesterol, the "bad" cholesterol, is primarily utilized only by the liver, not for other bodily functions like hormone production or energy. Contrary to some concerns, lowering LDL cholesterol does not appear to increase the risk of hemorrhagic stroke and may even reduce all-cause mortality and dementia. 

Dr. Bishop emphasizes the importance of considering lifetime risk for coronary artery disease rather than just short-term risk, advocating for earlier intervention. He also discusses Obesetrapid, a potential new cholesterol-lowering agent, and explores genetic factors contributing to longevity in "blue zones" like Campo di Meli and Le Bon Sul Garda, specifically mentioning mutations in the ANGPTL3 and Apo1a Milano genes. Finally, he touches upon CRISPR therapy as a future possibility for treating genetic cholesterol-related disorders. Dr. Bishop encourages listeners to share and like his podcast to help spread awareness about heart health and invites them to join the Healthy Heart Network for resources on managing heart health and reducing heart attack risk.

Takeaways:

  • LDL cholesterol, often called ‘bad cholesterol,’ is exclusively utilized by the liver and not by other bodily functions like hormone production, vitamin D synthesis, or energy.
  • Data from hunter-gatherer tribes and ancestral primates shows significantly lower LDL cholesterol levels compared to modern Western populations.
  • Current research indicates that lowering LDL cholesterol does not increase the risk of hemorrhagic stroke, contrary to previous concerns.
  • Studies like IMPROVE-IT and PCSK9 trials suggest that lowering LDL cholesterol can reduce all-cause mortality.
  • Recent research indicates that lowering LDL cholesterol may also reduce the risk of all-cause dementia.
  • Focusing solely on short-term risk calculations for conditions like heart disease can be misleading; lifetime risk assessment is more comprehensive.
  • Early intervention and risk modification for coronary artery disease yield greater long-term benefits.
  • Obesetrapid, a potential new cholesterol-lowering agent targeting the CTEP pathway, shows promise in raising HDL and lowering LDL cholesterol.
  • Genetic mutations, such as ANGPTL3 and Apo1a Milano, found in ‘blue zones’ like Campodimele and Limone sul Garda, are linked to lower cholesterol levels and increased longevity.
  • CRISPR gene editing technology holds potential for treating genetic cholesterol-related disorders by modifying DNA and altering protein production.

Australia, like the rest of the western world, has a heart problem.

Over 9 million people around the world die from heart disease every year.

Every 10 minutes, someone in Australia suffers a heart attack. And 21 lives are lost daily because of it.

The devastating fact in all of this is… 

Almost every one of those cases could have been prevented. 

This podcast is for anyone who wants to improve their health literacy and gain information to help them make the best decisions about their risk of heart attack, their cholesterol, blood pressure, risk of diabetes, weight loss and general health. Join me on my personal mission journey to prevent Heart Attack on a global scale. If you like this podcast, I would be honoured by a 5-star review and appreciate if you let your friends and family know about this podcast; you may even save the life of someone you love!


Are You at Risk of a Sudden Heart Attack? How Healthy is Your Heart? Really?

Heart disease is the #1 killer in the Western World. In Australia, someone dies every 28 minutes from heart disease. That’s 51 people a day. In the US, someone has a heart attack every 40 SECONDS! Fortunately, many heart attacks are preventable. However, regular exercise and eating healthy are no guarantee you won’t succumb to this silent killer.

  • 94% of Australians have at least One Risk Factor for heart disease.
  •  59% of Australians have been Touched by heart disease.
  •  Yet only 3% of Australians have had a Full Heart-Health Assessment in the past 12 months.

Do the free heart check today at www.virtualheartcheck.com.au


Join the Healthy Heart Network and become part of our growing community!

Do You Want to Improve Your Heart’s Health and Reduce Your Risk of Suffering a Heart Attack? Join The Healthy Heart Network For Only $5 Lifetime Access (Valued at over $55)!

The Healthy Heart Network is designed to help members:

  • understand the present state of their heart’s health
  • recognise their current level of risk of suffering a heart attack
  • Learn the positive steps they can take to improve their situation

Visit https://healthyheartnetwork.com/ and click on the JOIN THE FAMILY BUTTON

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