Welcome to Doctor Warrick's Podcast Channel. Warrick is a practicing cardiologist and author with a passion for improving care by helping patients understand their heart health through education. Warrick believes educated patients get the best health care. Discover and understand the latest approaches and technology in heart care and how this might apply to you or someone you love.
In this podcast, Doctor Warrick Bishop discusses fish oil and its benefits for heart health.
Fish oil contains two main components, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are believed to lower triglycerides, reduce insulin resistance, and reduce inflammation. However, there is not a lot of data to support the benefits of fish oil at low doses. Two major trials, the Reduce It and Jealous trials, have shown that purified EPA can reduce the risk of heart disease in high-risk individuals with raised triglycerides. However, similar trials using a combination of EPA and DHA have not shown clear outcome benefits. For individuals with central adiposity, prediabetes, diabetes, or significant coronary disease, a fibrate agent like phenofibrate (lipidyl) can be beneficial in reducing the risk of complications. Eating fish remains a good thing to do, but the interaction between EPA and DHA within fish is unknown. If you have high-risk cardiovascular disease and raised triglycerides in a pre-diabetic or diabetic status, EPA would be beneficial for you.
Phenofibrates are an absolute must for preservation of peripheral blood vessels and microvascular circulation in individuals with raised triglycerides and diabetes.
- Fish oil is believed to be good for the heart, lower triglycerides, reduce insulin resistance, and reduce inflammation.
- Fish oil has two main components: eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA).
- High doses of EPA have been shown to reduce the risk of heart disease in high-risk individuals with raised triglycerides.
- The combination of EPA and DHA has not shown clear outcome benefits for the supplemental group.
- The benefit of EPA is yet to be negated by DHA.
- Fibrate agents like phenofibrate (lipidyl) have a remarkable role in reducing some of the microvascular complications of diabetes.
- Phenofibrate reduces the chance of individuals with diabetes becoming blind and reduces the chance of amputation, particularly peripheral amputation of the feet, toes.
- Eating fish remains a good thing to do, but no one has looked at the EPA, DHA interaction within fish.
- If you have high-risk cardiovascular disease and raised triglycerides in a pre-diabetic or diabetic status, then EPA would be beneficial for you.
- If you have raised triglycerides and diabetic, then phenofibrates, i.e. lipidyl, are an absolute must for preservation of peripheral blood vessels, microvascular circulation, and maintenance and stabilization of your retina so you don't go blind from your diabetes.
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