EP16: The Art Of Good Medicine

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Welcome to my podcast. I am Doctor Warrick Bishop, and I want to help you to live as well as possible for as long as possible. I’m a practising cardiologist, best-selling author, keynote speaker, and the creator of The Healthy Heart Network. I have over 20 years as a specialist cardiologist and a private practice of over 10,000 patients.

EP16: The Art Of Good Medicine - Summary

Dr. Warwick Bishop is a practicing cardiologist and author who hosts this podcast dedicated to helping patients understand heart health through education. In this episode, Dr. Bishop discusses a chapter from his book exploring how evidence-based medicine works in practice and the limitations clinicians must navigate when applying scientific findings to individual patients. He argues that good medicine requires balancing rigorous evidence with clinical experience and personalized patient care.

Key Takeaways:

  • Evidence-based medicine provides scientific assessment of treatments, but study complexity means many confounding variables cannot be controlled or matched between patient groups.

  • Medical evidence reveals what works for the "average" patient, but individual patients often fall at the extremes of the range and require customized treatment approaches.

  • Some medical interventions cannot be tested through randomized controlled trials because withholding them would be unethical (such as early antibiotics), leaving gaps in the formal evidence base.

  • Study design flaws can undermine evidence validity—for example, using dosages of treatment agents that are too low to produce measurable effects.

  • The evidence base is inherently historical and can become outdated as new technologies emerge that shift our understanding of existing data.

  • Conflicting research results on the same topic (such as vitamin C effectiveness) create ambiguity about which evidence to trust, even when both studies appear well-conducted.

  • Good medicine is an art that combines three essential elements: an experienced practitioner, knowledge of the current evidence base, and understanding of the individual patient's unique needs.

  • The best clinical outcomes result from experienced doctors integrating scientific evidence with personal clinical judgment to create customized management strategies for each patient.

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Transcript English

**EP16: The Art Of Good Medicine** **Dr. Warwick:** Welcome to Dr. Warwick's podcast channel. Warwick is a practicing cardiologist and author with a passion for improving care by helping patients understand their heart health through education. Warwick believes educated patients get the best health care. Discover and understand the latest approaches and technology in heart care and how this might apply to you or someone you love. Hello and welcome to my consulting room. I'm Dr. Warwick Bishop. Today, I'd like to tell you a little bit about one of the chapters in my book that you might find interesting, a chapter I've called "The Art of Good Medicine." In that, I talk about how we use evidence-based medicine, which is the scientific assessment of how we evaluate treatment, therapy, and responses. The evidence base, when we look at a particular subject or area, can sometimes be very complicated during studies. We can match up all sorts of things: age, sex, blood pressure, diabetes. Lots of these factors are important to match up, but there are many things we can't match up. So, the complexity of these situations will always exist in the studies that we perform. We could, for example, randomize many people to two different arms of an intervention, only to subsequently find out that some people within those two arms like peanut butter, for example, and other people don't like peanut butter. Some are left-handed, and some may wear spectacles. Do those things impact the way we deal with the evidence? Well, I'm using sort of light-hearted examples, but it is possible that those variations of complexity make it very difficult. The other thing with evidence that's difficult to sort out is that the more we study a group or a population, the greater we are likely to get an answer for the average person. Well, I have to say to you, quite commonly, the people who walk in through my door are not average. They're either at one end or the other end of the range. And for that very reason, they're seeing me to try and figure out what suits their needs the best. So, the evidence base gives us a distillation of average, not necessarily the answer for the extremes. We've got to remember that when we look at the evidence base in medicine, sometimes the study just hasn't been done, and that's because it would be unethical. Antibiotics, when they were first used, were not randomized, and that's because they worked so well that it would have just been unreasonable not to treat everyone with them. So, if we were to look at the evidence base for the initial use of antibiotics, we would find nothing to support that they worked. Yet, there is no question that they clearly do work. A trial was written a number of years ago called the parachute trial, for want of a better term, and this trial made that point: parachutes have never had a randomized control trial to demonstrate they work. Yet, we accept that they do. So sometimes, in the evidence base, the study's just not done. One of the other things about the evidence base that's important to consider is that sometimes the study design doesn't necessarily achieve the goal because it wasn't an appropriate study designed for the question being asked. A really simple example of that might be using a very low dose of the active agent that just doesn't do the job. We also know that the evidence base is historical. It can only be implemented into therapy after years, generally of observation and study. What happens is that time can erode that evidence base, and things like new technologies can suddenly shift the way we look at that information. One of the other things about the evidence base is that we sometimes see conflicting data. So, the role of, say, vitamin C, for example, in some studies may look really encouraging, while in others, it may not be very encouraging. Well, which one do we believe? Particularly if both sets of trials look like they were well conducted. Complicated, isn't it? Well, in amongst all this evidence base, what I would like to put to you is that I think good medicine is a distillation of a number of things. The first thing is you need an experienced practitioner, someone who's looked after patients, treated patients, and understands responses to different interventions. So, in my opinion, the art of good medicine starts with an experienced doctor who knows the evidence base, who knows his patient and their unique requirements and needs, and pulls together the experience, pulls together the evidence base, and addresses the needs of that individual patient to bring together the best possible management strategy for that patient. I hope you have your own thoughts on the art of good medicine. Remember, I cover it in my book with a few other interesting topics as well. I hope you've enjoyed this little discussion. I really do wish you the very best. And take care. Thank you.